This is going to be a tough one to answer:
Can you describe the AVERAGE house in Santa Maria? In Reno?
You can ascribe the bedrooms and the bathrooms; but what's the $$/sqft? Hardwood floors? Updated kitchens? Size of the Lot and Landscaping? Taxes and Schools?
And once you've got the Average or Median; what will that tell you?
Are the job opportunities for both cities the same?
Where do you WANT to live?
Good luck and may God bless