Sorry to hear of your concerns and your wife's cancer.
My suggestion would be to talk with a Realtor that knows three things:
1. Your home
2. Local market trends and values - what buyers are looking for in a home
3. Your personal situation.
I would be happy to refer you to a top Realtor in your area that could help analyze your situation and offer your options, pros and cons, then your family can make the decision that is best for you. No cost or obligation.
Best of luck to you.