Yes, it can be a drawback in the State of Wisconsin. However, I have lived in a no-basement home since 1985 and I do not miss the basement at all. You have plenty of square footage and storage, so I'm assuming that for you, it won't be a problem.
My home is not on a slab either. I think the important things to look at are the age of the home. What does the floor currently look like? Are they uneven? Are they heated?
Mechanical differences vary from home to home without basements in this area. Some have the plumbing running through the walls and some are below the home and some actually run through the floor. It might be important for you to try to obtain the original plans or perhaps a neighbor to gain further details on this particular home. Make sure you get a qualified home inspector and don't over pay. You said, "it seems to be worth the asking price." If you have a Buyer's Agent ask them to do a market analysis for you to make sure you are not overpaying.