Yes, there are several loans available with no or little down payment. However, there is certain criteria that needs to be met.
Check out my blog here on Trulia to learn more about the homepath program:
Or, follow the link below to the GalleonProperties.com website to read more.
There is also, FHA which requires 3.5% down minimum or a USDA loan which allows for 0% down.
You can research each program to see if it fits your needs.
Best of luck finding your first home!
Galleon Real Estate