You probably cannot:
You should be talking to a Real Estate Attorney; primarily because Missouri is a RECORSE State, meaning that the Lender can file a Deficiency Judgement against you.
There may be exceptions and loopholes, so you should get local advice.
One thing you may be able to do, is offer the Lender a Deed-in-Lieu in exchange for a letter from them absolving you of the debt: They may not accept, but you can try; talk to the attorney.
Understand that most lenders and probably the Government, will not consider your predicament to be a "hardship".
Good luck and may God bless