Great question! First of all, she needs a sales license. That's her jumping off point.
Next, I would ask her where her passion lies. Each aspect of real estate has its own unique qualities, and hence, its own set of buyers and sellers. Does she like to crunch numbers? Very analytical? Maybe she should work the commercial side. Loves to talk with lenders? REO and Foreclosures, or asset managers. Very emotional, and a "people person"? Maybe first time buyers. What is her age and social circle? There are hundreds of niches to be served by the right agent, but above all, it takes a passion for what you are doing. You must be in it to serve.
Real Estate is eminently rewarding, but it is not easy, and not for the thin skinned. She must be able to know her own self, and handle rejection.
I would love to talk with her, and give some mentoring advice. In addition, I would suggest she go to http://yourcoach.com to see how the very best in the business are being coached.
The Bremner Group at Coldwell Banker
Web Reference: http://www.TheBremnerGroup.com