In addition to the answers below you may also want to check out the Mint Collection at 410 Jessie. http://mintcollectionsf.com/press.html. The Tenderloin/Tendernob area is undergoing a revitalization as well and if you have a long term (5 years plus) plan that will make for a good investment. Good luck!
This link is from a 2003 BizJournal article, so you can see that unfortunately change can be slow: