I commuted 90 miles on the 405 and 10 freeways in Los Angeles (with the LAX airport in the middle!) for a few years. I got out of that lifestyle as soon as I got the chance and now enjoy a brief 15-mile commute in the lovely Bay Area.
I think it all depends on how much you enjoy living (spending time with significant others and pets, running errands, relaxing and such), how much you enjoy your job, and what the right balance is. It would take a lot for me to do the freeway flying thing again, but I'd do it for the right house and the right job.