If you are looking for a comparison of the areas, Harleysville is more convenient to the Turnpike. Souderton is closer to Route 309 for Heading North towards Quakertown or South towards Montgomeryville. For the most part they are both Souderton Schools which just built a new high school 3+ years ago. There is equal shopping convenient to both areas.
If you are looking for more detailed information, or if you would like to view homes in both areas to get a feel for them, please do not hestitate to contact me! I know the area well, I live there!
Emily Landis Torres
Pa Licensed since 1993
215-362-2260 ext 1793