Most of the people who have answered your question have good intentions but without knowing the complete story, it is impossible to answer your question definitively. I work in local government and I can assure you there are MOST DEFINITELY situations where you will either need a variance, a change in zoning or your request to rent your home will simply be denied because it does not conform to local ordinances.
For example, if you plan to rent your home and live in a detached garage that has previously been converted to living quarters, this is illegal in most jurisdictions and can result in fines or other penalties assessed against you as the property owner. If you plan to rent your home which you have subdivided into apartment type living quarters with a shared kitchen or kitchenettes in each apartment area, this is also illegal in most jurisdictions. If you plan to rent your home and occupy a recreational vehicle parked alongside or adjacent to your property, this is most likely illegal in most jurisdictions. As another person pointed out, if you live in an area that is part of a Homeowners Association, there may be restrictions or covenants that prevent you from renting your home as well. It is important that you fully acquaint yourself with the laws and conditions that govern the neighborhood where the property you'd like to rent is located.
I would suggest, BEFORE advertising your property for rental, that you contact the appropriate local entity (City of Las Vegas, City of North Las Vegas, City of Henderson, City of Boulder City or Clark County) and explain what you would like to do to make sure it conforms with that jurisdiction's ordinances. The names of the local departments that handle these inquiries vary from jurisdiction to jurisdiction but try Community Development, Zoning, Code Enforcement or similar departments to find the answers you need before you proceed.
Good luck and I hope it works out for you!