This could go in a few directions.
If your wife is disabled, does she get permanent disability payments? Depending on the amount she receives and your debt ratio, you may be able to qualify for something.
As for yourself, If you are unemployed but looking to return to the workforce, we would want you to be back at work a full month and preferably in a fixed salary position.
It is plausible that you might be able to qualify with a non occupant co-borrower with a Freddie Mac approval. If you have a family member that is willing to co-sign, this might be an option. I suggest you contact me and I'll be happy to discuss any and all possibilities with you.
Either way, I wish you and your wife all the very best.