Drive time to get to Tampa International Airport from 7335 Lincoln Park Ln, Port Richey, FL, according to my own personal experience having lived near by Port Richey, is 45-50 minutes. Google Maps list 3 different routes to choose from. You can check out the Google Map I created for you at the link posted in the web reference.
WARNING: Taking Hwy 19 will always be longer than expected, also, it will cost about $4.25 to get to TIA on SR 589 but it is well worth it in my opinion.If you are making the trip often it would be worth purchasing a Sunpass.
Florida Licensed Real Estate Broker
Tampa Bay Area, Florida