The big decision maker will be cost. To do a glass enclosure right, where you don't have the humidity issues, you're looking at 10 - 20 times the cost of a screen enclosure to do glass. A typical screen enclosure will cost around $10,000. The code compliant glass room, is going to need climate control and impact glass windows. The company I know closely in Orlando area says you're looking at $150,000+ for that.... but it then becomes habitable living area of sqft added to the house.
Kenneth Wilson | http://www.flscreens.com/knowledge-center/