There have been no earthquakes in this area and a tornado hit North Minneapolis last summer, making it unlikely that another one will hit the same space. (Actually, the bit about the tornado is simply an old wives' tale.)
As far as 'safe' in other ways, I suggest that you drive around the area during different times of day and check on the statistics for the area on the internet to find out the information you seek. Your idea of 'safe' and someone else's idea of 'safe' might differ. This is something you would have to decide for yourself.