Getting with the lender is the only way. They will let you know everything you need in order to get the person of the mortgage. If you also need to get the person off of the deed, then you will need to put in a Quit Claim deed and both signatures will be needed unless the person you are talking about is no longer of the realm. Then you will need the death certificate for proof.
Hope that helps,
Terrence Charest, e-Pro