As some of the previous have "kinda" mentioned....there is not enough information provided here to provide an accurate answer. I have to agree with the advice that Dp2 mentioned. Great minds think alike once again.
Banks will basically not consider a short sale unless the payments on the property are 3 months late. If there is significant equity on the property or other assets which can be used to cure the issue, they won't do a short sale.
You have basically have 3 options:
1) Sell the property outright with either a Cash Deal or Terms Deal
2) Rent the property
3) Give up the property and receive a foreclosure
Obviously, #3 is the least effective method of getting rid of the property and not too many people would suggest/advise going that route.
There are many other solutions to sell your house:
Lease Purchase to a tenant/buyer
Wrap Around Mortgage
Contract for Deed
Giving it to a buyer "Subject-To" the existing financing
All of these examples are, of course, dependent upon you needing to get your cash out of this property to move onto another property. If you happen to have another place lined up to live, you may want to look into selling your house as a Lease Purchase (Seller Financing as Dp2 mentioned earlier). There are ALWAYS more tenant/buyers out there looking for a Lease-to-Own property than there are sellers offering them.
No matter what route you take, PLEASE find KNOWLEDGABLE people who can put the deal together for you, be it an EDUCATED Realtor, Attorney, Lender, Sophisticated Investor, etc so that it can be less stressful and more successful. I may even be able to help you or to point you to some people living outside of Charleston who may be able to assist you.
All the best to you Brian....