It depends on income and debts. I personally wouldn't purchase something up to the amount I'm approved to. I'm approved for much more than I would spent. You have to take into account to cost of owning a home, repairs and emergency account. Also if you are planning on having kids soon the add costs. You can use mortgage calculator online and enter the amount with down payment, interest rate ect to figure out what the monthly payments would be with insurance and PMI. With that add up those costs plus all other costs ie. car payment and insurance, internet and cable, cell phone, amount spend on food a month and gas. You can get an idea and figure out what your approx total costs would be just for basics at the price.
People tell you find out how much you can get pre approved for but I would advise to be careful if thinking about spending the amount you have been approved for.