The most popular answer to this age old questions is "Location, Location, Location". Most of the agents responding to this post have also included location as part of their answer and there is good reason for this. It is a pretty good general rule of thumb. That said, I believe that desirability is really the result of three factors; Location, Condition, and Price. The key is to balance these three things. Since location cannot be changed, you need to focus on the other two. Poor location can be overcome if the right adjustments are made in regards to price and/or condition. In this current market I would recommend concentrating on price.