Your question is very vague. Because of the higher real estate price values of properties along the Intracoastal (both homed and condos) anywhere from Palm Beach County down to Miami are, therefore, mainly attracting the more affluent members of society. Thus, those neighborhoods are generally much safer than the mainland.
Next to your username given hereon Trulia, it states that you are from Fort Lauderdale and the Intracoastal travels east along the ocean through Fort Lauderdale unless you mean a traveling distance to downtown Fort Lauderdale. However, to ensure you get that extra sense of security, I recommend you buy a condo in buildings that have garaged parking and 24 hours manned security. For homes, I suggest Coral Ridge Country Club and Olde Coral Ridge, the Landings, Sunrise Harbor, the 7 Isles, Sunrise Key but if you really want the added vigilant security, look in prestigious Bay Colony off Bayview Drive or the Sea Ranch Lakes off A-1-A where homes start in the millions and the guards are armed to the teeth - they don't even let mosquitos get by.