I agree with Rick in that the area off Narcoosee Rd. is going to see the most growth in the next 10 years because the new medical school and Burnham Institute will create demand for housing in this area. There's also some old faithful areas that have always been good. While the Narcossee Rd. area is more of a speculative buy, Dr. Phillips, Windermere, Winter Park, and Lake Mary have always done really well for appreciation compared to the rest of Orlando. Winter Park tends to have more older homes but new homes can be found a Baldwin Park and Windsong. Orwin Manor is my favorite neighborhood for older homes in Winter Park. Alaqua Lakes in Lake Mary is a good place to start but it is pricey here. In Dr. Phillips and Windermere, there's just a ton of choices for new and older homes. I believe Windermere has recorded the most number of sales of homes that cost more than a million dollars in Central Florida. You can check out my blog to get an idea of Windermere and Dr Phillips. It's a great time to buy with a 10 year time horizon. Some of the best deals can be had in this depressed market.