I would suggest trying the suburbs with the best highway access first. For example, Manheim Twp,, East and West Hempfield Townships, All have excellent direct access to major commuting routes 283, 30, 501, 222, and 272. This makes for easy access to Harrisburg, Reading, York, Lancaster City, and even Baltimore and Philadelphia. These properties may be slightly more pricey, but would command higher rents if in good condition. For long-term investment, they will appreciate at a respectable rate and resale is frequently easier for suburban properties.