What is your reason for wanting to negotiate your interest rate? If you've suffered some type of hardship, usually lenders will work with you. Your hardship needs to be documented as well as your financial statements, income and expenses. Loan modifications are being done, but due to the high rate of foreclosures and short sales, loss mitigation departments are over loaded with files. If you want to negotiate the terms of your loan, you need to do your homework and provide sufficient evidence of why they should negotiate your terms and make sure your finances support what you are negotiating. Hope this information helps....let me know if you need more information. Good luck!