It depends on how you feel about commuting 'cause the commute can be WICKED. Your wife will be sitting on I45 about 2-4 hours a day...wait, what? Yeah. Not fun. The realtor below me mentioned Cinco Ranch. Lovely area west of Houston but the commute is gonna be a killer there, too.
The Heights is where you want to be if your wife works downtown. Great, safe area, the best location in Houston if you need to be downtown, and good schools. The Heights neighborhood (77008) has terrific triple decker townhomes and bungalows galore.
If I made more money and was forced to live somewhere else in Houston, Memorial would be it. Memorial Drive runs for miles through Houston and both upper and lower Memorial are bar none-beautiful homes on acreage, privacy galore, the best schools, and like-minded people.
Again, it depends on your budget and priorities. What attracts you to Kingwood? I am an individual and not in real estate, just curious. Oh, and to answer your question, yes, Kingwood is a very nice area. Just look out for the random pockets of apartments where you generally are going to have a LOT more issues with quality of the people residing there (as opposed to someone that can afford and handle the responsibility of a house).