Hi Matt -
I'm not sure if you are still in the market, as this post was done about a year ago. However, I will still shed some light on this question, since I am an expert in this area.
I live in Wicker Park, near Leavitt and Schiller and my best friend lives at Artesian and Hirsch, which is about 3 blocks from your prospective location. The area, in general, is safe. A lot of people have concerns about moving West of Western, but that area has been gentrifying rather quickly. The closer you get to Humboldt Park, the less safe it gets, in my opinion. I would be lying if I told you that my friend and his wife haven't heard their share of fireworks or gunshots at night, but it is the city, and these things are not that uncommon.
If it was up to me, I would search for a home in Wicker Park or Bucktown, but obviously the price point will begin to go up.
I hope this helps.