After 22 years of working with 1000's of buyers, I believe it's buying what you want provided your not over extending yourself.
If you purchase a home your happy with and like, you'll always make it work. If you compromise you will regret your decision and likely find yourself looking again in a few years. This is a big purchase and not typically very liquid. BUY WHAT YOU LIKE!!!
Get qualified, identify whats important and look within that price range.
Wish you the best of luck. :-)