I don't think any one area has a monopoly on northern light.
In lower downtown, I'm sure there are warehouses that have been converted to lofts. In fact, there are condos called lofts down there.
As others have noted, you haven't really stated what are the things you are looking for, and that limits how helpful we can be. Readers who want to post questions, please supply more information when requested. We're at our best when we have information.
My husband is an illustrator and he says an artist wants to be close to his subject matter and other artists. That would be the Capitol Hill and lower downtown areas. In fact, the general area running from Santa Fe and Broadway over to University along 14th is a very vibrant and interesting area. You can rub shoulders with other artists there, visit the Modern Art Museum as well as many galleries in this area.
You might also check out Loveland, Longmont and Boulder for their art communities. But, you asked about Denver. There is also the Academy of Arts in the area I described at the top. Denver has a concentration of universities at the Auraria Campus. My husband studied fine arts at Metropolitan State College years ago.
There are some inexpensive rents in this area. I love the restaurants. Younger adults migrate to this area for its lifestyle.
PML of Longmont, CO
720 810 0683