Short answer is yes. See below my comments.
1 - typical FHA financing requires 3.5% down. Sellers are allowed to contribute up to 6% towards buyers' closing costs.
2 - Fannie Mae offers HomePath which requires a minimum of 3% down payment. Other benefits of HomePath are no appraisal required, no mortgage insurance, available for primary residence, vacation homes, and investment homes. Available only for properties owned by Fannie Mae. Usually not a problem because Fannie has a huge inventory of homes in our area.
3 - Freddie Mac has HomeSteps which is not a loan program (although some people gets confused). HomeSteps key benefits are up to 3.5% of closing costs assistance, 2-year home warranty, and 30% appliance discount.
4 - Many cities have special programs to help first time home buyers or buyers of distressed properties. So depending on where you want to buy, you may have access to one of those programs. For example, Phoenix has a very interesting program for buyers of distressed properties where they offer up to $15k no-interest loan towards down payment and closing costs. Each program will have its specific eligibility requirements. I wrote a blog post about the Phoenix program I mentioned above. You can check it here -> http://www.myfirsthouseaz.com/blog/?p=767
I hope this helps.
Jose Dias, REALTOR
Realty One Scottsdale