Courtney, I know you asked this question a while ago but figured I'd throw in my two cents.
Erie definitely has settling, though if you've been looking at houses you might notice that every neighborhood has its own aging process. This has to do with the mitigation that builders did during construction. Some areas, like Meadow Sweet Farm and Country Meadows, are really minimal overall. You'll see it primarily in walkways and driveways. Just east of those subdivisions there is significantly more settling.
As far as the house you're interested in, your agent should be able to direct you to a certified inspector who can provide you with an objective report on the house's condition. No need to run...yet!