If you have a valid hardship such as bad health and the value of your home is less than what is owed on it, you may be able to sell it as a short sale. This will have a far less impact than a bankruptcy or foreclosure. Fannie Mae recently came out with new guidelines and policies https://www.efanniemae.com/sf/guides/ssg/annltrs/pdf/2008/0816.pdf in regards to short sales, bankruptcies, and foreclosures.
You should hire a compent real estate agent familar with the short sale process to assist you. Go to http://www.greetingsvirginia.com/custom10.shtml to view recent short sale APPROVALS in Northern Virginia from banks that Dan and Traci & Consultants with Keller Williams Realty have negotiated