I live right on the corner of 145th and Bradhurst. I think you just need to use common sense and stay aware when walking down Bradhurst, or any street at night. No ipods or cellphones, just stay alert to what's going on around you.
There are several police precients in the area, the metro station has a police station on site and there's a station on Frederick Douglas at 147th.
If you're concerned, I might walk down to that street and then take a cross street to Bradhurst, but overall, I've felt safe and secure in this neighborhood.
Welcome to the neighborhood!