That's a great question. It really depends on many factors including your income, credit, down payment, and work history. Also, the homes' property taxes, insurance cost and whether or not it has rental income. That's just a partial list.
Your best bet is to meet with a local, experienced and licensed mortgage professional for a free mortgage preapproval to learn exactly how much house you can afford. You may want to start with your current bank, ask family and friends for referrals and also check reviews on Trulia/Zillow.
All the best.