It is always a possibility to negotiate a lower price. The big things that are going to be a factor are:
*Is your offer the only one or are there multiple offers?
*When submitting your offer how does it look? Have you been pre-approved? did you include a pre-approval letter with your offer? are you asking for a long drawn out closing 45+ days?
*How long has the property been on the market?
*When your Realtor pulled comps on the property you like was the list price comparable to recently sold homes in the area?
These are going to play a big part in being able to negotiate a lower price. I hope this information helped, please don't hesitate to contact me with any additional questions.