You really need to research all of your options, interview many brokers, and find the place that "best suits you". But what exactly does that mean?
Do you have a strong business background and marketing knowledge? Or do you need a mentor to help you determine your business plan?
Are you a strong self-starter that can work from anywhere? Or do you need/want to go in to an office every day for the support, available training, etc.?
Do you have a lot of money set aside for startup expenses? Or do you need a brokerage that provides signs, lockboxes, leads, marketing assistance, etc.? (And make sure you find out what kind of leads and how many they do provide). Some brokers have lower fees and you pay more when you close a deal. And some brokers have great commission splits, but charge monthly fees.
Are you looking for a brokerage that is forward looking and will support you if you want to focus heavily on internet marketing for building your brand and gaining exposure in the marketplace? Or do you have a large number of local contacts and plan on marketing the old school way? Some brokers will tell you to focus on your sphere of influence and discount any internet marketing efforts -- even in 2010! You need to do both.
Do you want the name recognition of a large brand behind you? It can benefit you. I personally have received calls from people because of the name brand. But there are fees associated with the brands. You need to decide if you think the benefit outweighs the costs for you.
Make sure you find out the answers to these questions as you are researching different companies and interviewing companies.
You need to determine how you want to run your business, and then with your plan in place, determine which broker "best suits you".