BY ALL MEANS YES!!!!!
Sometimes a client and agent are simply not a good fit. It does not mean either is a bad person. Some people just do not "click".
I have only parted ways with a client once, and it was hard decision to make. He was a well qualified small investor with whom I had worked with many times. But after a while I realized he treated me more like his personal assistant than the real estate professional I am. The business relationship had become too one sided. I was bending over backwards to meet his needs, and he Never seemed to appreciate my efforts, or have any kind of respect for my time.
My business model is to close an escrow on EVERY client, so to part ways with one was very hard, but it was the right thing to do.
Kawain Payne, Realtor