That's usually pretty easy.
First, go online and look up the tax record. For instance, if I wanted to find the owner of a house in Huntsville, Alabama, I'd search for "Huntsville AL tax assessor." That'd bring me to http://www.co.madison.al.us/ From there, I'd click on "Property Assessment Online." (Most counties and cities have online tax records.) From there, you can search a particular address.
If that doesn't work, knock on neighbors' doors. It's very likely that some of the neighbors will know who the owner is and where he/she/they currently live. I've done that a lot, and almost always succeeded.
If the property has been foreclosed upon and the online search information hasn't been updated, then contact the local tax assessor's office. As soon as the new deed is filed, it's public information. Or just go down to the courthouse and ask one of the clerks there for assistance.
Hope that helps.