It depends on what you are looking for as to what the best is. if you would like walkability to restaurants and stores the closer to Telegraph or 40th is best. If you want a more residential area Lawton and Webster are quieter streets. If you need to be within a BART station, the are around 41st and along 40th are a better location.
Price range is a factor as well. Fortunately Temescal has a variety of condos and single family homes to choose from with all the other amenities of the rapidly changing area. It's a vibrant neighborhood.