Since there is a lot of inventory, just make sure your agent runs the comps to validate the price you choose.
In Canton you have a geographic isolation because the neighborhood is bordered by the Harbor and Patterson park. It is a fundamental principal of real estate where areas that can be isolated will always be worth more.
School districts also vary in Baltimore city so even if you don't have kids the school district will affect the value of homes in certain neighborhoods.
All in all East Baltimore is Experiencing urban renewal I don't think you will go wrong in the 21224 zip code.
Robert A. Small
American Mortgage, Incorporated
Toll Free (888) 270-9808
Cell (443) 417-8944
Fax (206) 350-4491