Not having a job yet is not necessarily a problem, however you can't just go ahead and move down there, settle in, then find a job.
If you get a job offer in writing, and have a signed offer letter outlining your start date and rate of pay, then as long as it is in the same line of work and you qualify with that income and credit you should be OK. Usually you have to begin work and begin getting paid prior to the first payment being due
If you are moving to Michigan, this website contains homes for sale and lease in southeastern Michigan. http://moveinmichigan.com Sample real estate forms are available on the website below.
As long as you get a job in the same line of work you have been doing for the past two years you will be ok. If you just graduated from college or will be soon, they take that into consideration too.
Hope this information helps you.