If you don't ask, you don't receive.
It depends on whether they're finally ready to get rid of the property and the type of deal they have with the seller, as to how aggressively they will respond to your offer.
As real estate is local in nature, your offer amount would depend on researching comparable sales in the area, the amount that you are qualified for and the relos asking price. All of those factors must be taken into consideration.
Best wishes to you.