There will be noise and patterns could change over time.
Another thing to consider is resale value. Future buyers will have the same concern that you are having.
There is no reason not to buy if you get a fantastic price. However, ask yourself if you will be questioning your decision for years to come. A train is like an elephant in the living room. Even if you try to ignore it, you know it is still there.
May I wish you the best.
Jeff Masich, Realtor
Arizona Homes and Land