A person or primary person can deed out of the property. If there is a loan against the property and they are on the loan they will still remain on the loan even though they deed off unless the other party (s) do a refinance.
Sometimes in that case, a Power of Attorney could be established. In these such cases, it is best to consult your attorney to see what your options are.
The person who will be removing their name from the deed would have to agree to do so, by signing off on the new deed that reflects the transfer to another party.