There are some real nice houses there and most are set back pretty much from the road.
Wyckoff really does not have any "bad" sections. I have worked here as a realtor for 10 years and I know the town. Parts are considered more "desireable" than others based pretty much on which primary school the street feeds to but thats peoples opinion. I prefer to be away from Rte 208 as its obviously pretty noisy. The east end (which includes Lafayette ave) is a bit remote from the center of town but then Wyckoff does not really have much of a downtown. In fact the east end is close to Midland Park which has more of a downtown area
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