Here are some things to consider....
If you do build here, will you become so committed and in love with your house that moving to MA will be out of the question?
Why move to MA anyway unless someone is offering you a once in a lifetime opportunity? I don't think you can beat the Knoxville area for a place to live. We have seasons but we don't have extremes. If there are things in MA that you would like to do, you don't have to own an airplane to take a ride on it.
Think about it...would it be easier to sell a house or a lot? If you were shopping which would appeal to you more?
Everyone that I know has a crystal ball sitting on the shelf that is cracked, broken or waiting on back ordered parts. There is no good way to predict the future, especially that far down the road. Take a look at the last 3 years. Who saw all of what is going on now coming? There have been so many changes that have impacted the real estate market in the last year from political to economic to world events. There is just no way to predict the future 2 or 5 years from now.
Finally, if you are looking to make money to support your decision to move to MA, there are a lot more lucrative investments with less risk out there.
Take a look at the link referenced below. I think it has some things in it that might be thought provoking for you.
Hope this helps.
Lets say that houses are selling for $200 per squarefoot; what will it cost you to build now?
Lets say $150 per square foot. Add in the cost of the lot and find out what you would have.
I would bet that you will be above the average now!
And I would bet against much of an appreciation over just two years.
Good luck and may God bless