As far as I can see there is nothing unique about Southeast Raleigh. With the exception of the number of oak trees. There seems to be a concentration of oak trees located in Southeast Raleigh.
Being a native of Raleigh I can truthfully say that the most unique part of Raleigh is West Raleigh, and the most beautiful part of Raleigh (in my humble opinion) is of course North Raleigh. In particular , BayLeaf.
NC State University is located in SE Raleigh so there seems to be more of the university influence, student housing (investor rentals), the state fairgrounds, and older commercial/warehousing segments, though that sort of zoning is spread around the city. There are a number of nice neighborhoods and parks also, and it is easy to find a home where the aforementioned aspects are not an influence. Depending on where one might work and commute, that part of town is a good location to go east, south, or west of town and it would be in the worst of traffic heading towards RTP locations as it blends in with Cary traffic flow. Is there a reason that you are focusing on the SE part of town?