Some will price the property aggressively and artificially low to attract attention
Others will price it with a little "padding" to allow for negotiation with low offers
Best that you engage a realtor to help you by getting comparables to determine the fair market value of the property. Then use THAT as to guide you in writing an offer. For example, if the property is priced well but hasn't received any offers, then you may want to offer a bit less.
But if your market is hot, hot, hot....you yourself may want to write an aggressive offer to be more competitive in a multiple offer situation.
If you're working with a realtor, put your realtor to work for you by getting you those comps. If not, give me the address of the property and I'll try to help.