David Stefik, Stefik Realty, http://www.stefik.com
If you are looking for great schools...
The best public high school in the area is City Honors but you have to live in the City in order to have your student attend. If you consider the city, I think the best location is along the Elmwood strip between Allen St and Amherst Street. Neighborhoods are fantastic and culture and food is solid. Oh, did I mention City Honors was ranked 4th best public high school nationally?
If school is not an issue, Cheektowaga has mediocre or worse schools, but has some great neighborhoods where there are plenty of retired couples, every yard has been landscaped and sometimes you can find more home for the money. I am currently living in Cheektowaga.
I grew up in Orchard Park. I think it was one of the best places I could have. Great schools, great environment, and great inspiration. I grew up a short drive from the Bills Stadium. It was the type of area where me and my friends rode our bikes 3 miles to the village and went to the local sports card shop. Dominated by mostly doctors and lawyers and old farm land, Orchard Park is a great place to live.
East Aurora with its old five and dime, and the best toy manufacturer in the world (Fischer Price) , has a lot to offer. It has a smaller town community with a modern suburb's power.
Hope this helps.
If you want a little more rural with the occasional Farm then Clarence.
Also, Williamsville and Clarence have the top rated schools in this area. Property taxes are really high in Williamsville though.
~best of luck!!
Orchard Park is beautiful.
If you are a senior looking for simplicity, low taxes, ranch living, nice neighborhoods try Town of Tonawanda.