For a single family home, the sales comparables would show you what the closest matched home recently sold for. This gives you the best estimate of what somebody would pay for your home. But, it still has serious limitations in that the sold price is a snapshot of the market in history, usually at least 3-4 months ago. So, prices may have moved significantly in the meantime.
For an investment unit, the income approach is best since the largest target market of buyers are other investors and they value properties based on income generated.
The replacement cost approach is really useless in real estate, except for the insurance company's sake. A 50 year old home may cost $500K to replace but has only $50K in value to buyers.