If the right of way is solely for the use of the house at the rear and has no impact on your enjoyment of your home and the property then the answer would be no. Although it is used infrequently it could be used full time and you have no recourse.
Could it affect the resale of the home, depends on many factors, most have to do with what I state above and the value of your home in the market presently, as the present value could be higher without the easement and is priced accordingly.
2) If the right of way is simply a driveway to another home that shouldn't impact your use of the home of interest. However, there are a few questions you should ask about the ROW, for instance, does the driveway cut up your yard in any way? Who is in charge of maintenance of the driveway (shared cost or paid by other home owner)?
Easements and ROW's are not uncommon so don't drop the property from your list until you have answered all the necessary questions.
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the right of way on the driveway and whether or not is an issue really depends on the potential buyer. If this one rarely gets used then it really is up to you and if you are getting it at a good fair price. Ask your buyers' agent that is representing you for his/her opinion (if you do not have one you should get one and it does not cost you anything). Some people care about a row and others don't so you will need to decide if it will be annoying for you to see someone using it every now and then. Have you seen other houses that you may be interested in without a row?. Also have your agent do a cma to determine value and make adjustments as needed for the row. This might be help you in making a decission. Hope this helps. Wen -- firstname.lastname@example.org
If you can find another home w/o this issue, go buy another home.