Your best bet is to connect with an agent and/or a developer/contractor for assistance. I have worked with a couple of developers who have done this type of work in recent years. If you seek out a commercial agent, be ready to SHARE your complete financials and business plan before they give you the time of day.
Give me a call or email and I can make some direct recommendations for you.
West Oakland may be a place you could look into since there is quite a number of lofts and warehouses in that area. It would be easier to find something that already functions as a live/work space than to get a variance.
Let me know how I can help....