It's one of the areas I would look at, but there are others such as West Los Angeles, and Culver City to name a few. For the best chance of finding the right property, I recommend that you retain a good buyer agent to help you.
When you say large home what is you requirement for home's square footage, bedrooms and bathrooms? Westchester is a residential area the majority for homes are under 2,000 sq. ft. living space but there are areas with new homes with living space over 2,000 sq. ft. Check for leases in Westchester. Suggested sites: Trulia, Zillow, Westside Rentals and Craigslist.